Redox-sensitive polymeric nanoparticles for drug delivery.

نویسندگان

  • Hanjoung Cho
  • Jungeun Bae
  • Vivek K Garripelli
  • Joel M Anderson
  • Ho-Wook Jun
  • Seongbong Jo
چکیده

Bioresponsive polymeric nanoparticles have been extensively pursued for the development of tumor-targeted drug delivery. A novel redox-sensitive biodegradable polymer with "trimethyl-locked" benzoquinone was synthesized for the preparation of paclitaxel-incorporated nanoparticles. The synthesized redox-sensitive nanoparticles released paclitaxel in response to chemically triggered reduction.

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عنوان ژورنال:
  • Chemical communications

دوره 48 48  شماره 

صفحات  -

تاریخ انتشار 2012